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Hi,

Seems like this thread is nearing its end in terms of productive discussion. It will be interesting to see how the protein strucutre prediction field progresses. Perhaps it makes sense to...

(1) plaidfishes: Interesting post. It's clear that you've though about this, but I guess I disagree with you in several areas, but perhaps it's just me.

First, protein structure prediction is...

Aegion: while I agree that drug design, etc may be a "long term goal" of the project and agree with you that this won't be happening in a few months, the real question is when will it be happening?
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Lots of posts and interesting things to respond to. I'll try to be brief on each.

plaidfishes: I think you might be missing the point in your FAH vs DF comparison. FAH is not doing structure...

Hi Scott,

Your questions are the right ones to be asking IMHO. Here's my answer. I'm sure the DF guys might have a different perspective and I'm not sure there is any "right" answer. Well,...

Dear Howard. Thanks for taking the time to reply. I personally really appreciate it. Moreover, I think others have similar questions as well.

I think we disagree on the need for sampling in...

Thanks for the info Howard (Brian?). It does explain a lot and thanks for taking the time to answer my questions.

You mentioned that

"We were able to obtain a 2.03 A structure for Villin,...

I think I can answer Scott's question. Distributed Folding looks to be addressing the structure prediction problem, whereas Folding@Home is addressing *how* proteins fold. Different questions.
...

I was just curious to hear more about the science of distributed folding. I'm a grad student at Berkeley, but hang out at Stanford too (my wife is there) and have heard many of the big names in...