I just recieved the following email from the CASP organizers with the latest information on the CASP7 eperiment which begins on May 10:
Dear Predictors,
CASP7 will begin May 10 with a single target trial followed by two
targets on May 11.
Some additional notes on this yearsÕ process:
MODEL ACCURACY
We will pay special attention to model accuracy predictions. These can
be submitted for own predictions in the regular CASP format (PDB
B-factor field) on a per atom basis. These should be error estimates in
Angstroms. In addition an overall score for a given model can be
submitted as follows:
REMARK SCORE 0.7
in prediction header, where SCORE range is 0.0 to 1.0 (1.0 being a
perfect model). Independently, model accuracy predictions can be
submitted on server models, usually available within few days of target
release, or on your own models in the following format:
http://predictioncenter.org/casp7/do...format.html#QA
The deadline for accuracy predictions on server models will be the
regular deadline for that target (typically 3 weeks).
In addition, to assess model evaluation methods on all CASP models
(i.e., including human expert predictions) we will be shorly collecting
software for a later assessment. Additional details will be announced
separately.
MODEL REFINEMENT
Special attention will also be paid to model refinement. In some cases
(CM/easy targets of less than 150 residues, preferably less than 100
residues), a single model submitted during the regular prediction window
will be selected for further refinement by others. Refinement window
will then open for additional 3 weeks. The usual refinement of own
models is still encouraged (using the unrefined and regular Ð for
refined models - model designations).
PREDICTION WINDOWS
Prediction windows will in general be shorter than in previous CASPs
(approximately 3 weeks). This is to adhere more closely to the
target structure release timelines adopted by crystallographers and to
minimize information leaks and subsequent target cancellations. However,
to allow assessment of methods requiring longer computation times, at
least some target deadlines will be extended. In such cases we will
still strongly encourage submitting models within the 3 week prediction
window. If information leak occurs after the initial three weeks but
before the assigned prediction deadline, evaluation of models will be
limited to those submitted within the 3 week window only.
PREDICTION OF FUNCTION
The format for function predictions is as follows:
http://predictioncenter.org/casp7/do...format.html#FN
Additional targets will be made available for this category of
prediction (targets for which experimental structures may not be
forthcoming).
MODEL QUALITY FILTERS
Human expert predictions with severely unrealistic geometry will be
rejected outright. The criteria for this are as follows:
More than 5% of CAs taking part in clashes of less than 1.9 Angstrom.
OR
More than 25% of CAs taking part in clashes of less than 3.6 Angstrom.
CA-CA clashes below these percentage values as well as segmented
predictions with more than 4 chain breaks (CAs adjacent in sequence
separated by more than 5 Angstroms) will be flagged (warnings issued).
The model will be accepted, but it might be penalized in the assessment.
Missing loops or other deletions are acceptable.
Server predictions with clashes will be accepted in all cases, but
similarly to the human expert predictions will be issued warnings and
might be penalized in the assessment.
--
CASP7 organizers