That's an easy one (even for me, I guess)
If you have 1 computer that is currently working on generation 181, then that PC has generated soms 80k points for you.
Seeing as your score is 780k I assume you have many more computers working for you.
If you have 1 generation buffered then that is the generation you're currently working on, gen 181 in your case.
You always have at least 1 gen buffered and that is the one your working on. So you are already auto submitting
Your client picks up where it left, so that would be gen 150.