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Thread: Need for quick 10,000 folds

  1. #1

    Need for quick 10,000 folds

    I noticed that I have always gotten my RMSD scores in the early stages of the generation set. I wonder if the quick 10,000 starting folds is necessary? Maybe it is better to just start with the regular folding. Non-scientific observation for sure.

  2. #2
    Senior Member
    Join Date
    Mar 2002
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    If you don't do the 10,000 proteins, then you won't have anything to start with. Gen 1 uses the best protein from gen 0 as its starting point.
    "If you fail to adjust your notion of fairness to the reality of the Universe, you will probably not be happy."

    -- Originally posted by Paratima

  3. #3
    I understand now, I just assumed that the program used the amino acid chain to fold and just kept trying to fold that chain at random.
    Thanks!

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